Disorders related to recurrent use of drugs other than alcohol that cause clinically and functionally significant impairment such as health problems, disability, and failure to meet major responsibilities at work, school or home. Diagnostic criteria include intense cravings; impaired control of the amount and frequency taken; persisting in use despite harmful personal, social and occupational consequences; risky use, e.g., driving or operating machinery while under the influence; increased tolerance and physical withdrawal symptoms.

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